| No. | 系列 | 代表品種 | 主要應(yīng)用 |
|---|---|---|---|
| 1 | m?PEG 系列 | m-PEG5~PEG12 -OH /-NH? /-Br /-N? /-COOH /-OTs /-SH | 多肽與小分子藥物側(cè)鏈修飾、ADC/XDC 連接子、PROTAC 連接子 |
| 2 | 甘醇系列 | HO-PEG5~PEG36 -OH、m-PEG24 -OH、m-PEG45/48 | 長(zhǎng)鏈修飾劑、脂質(zhì)體與LNP 輔料 |
| 3 | N??PEG 系列 | N??PEG3~PEG36 -OH /-COOH /-OTs /-CH?COOH /-Br /-NH? | 點(diǎn)擊化學(xué)（CuAAC/SPAAC）、ADC 連接子 |
| 4 | NH??PEG 系列 | NH??PEG3~PEGn-OH /-COOH /-CH?COOH /-NH? /-Alkyne | 多肽固相合成、蛋白質(zhì)修飾、熒光標(biāo)記 |
| 5 | Mal-PEG 系列 | Mal-PEGn-OH /-COOH /-NHS、Mal-Amido-PEG8 -NHS、SMCC | 巰基定點(diǎn)偶聯(lián)、ADC 連接子 |
| 6 | FmocNH/BocNH 系列 | FmocNH-PEG3~PEG24 -COOH、BocNH-PEG3~PEGn-OH /-Br | 多肽側(cè)鏈合成（GLP-1 類、C5 抑制劑類） |
| 7 | 功能性產(chǎn)品 | DBCO-PEGn、Poma-PEGn、Biotin-PEGn、VHL/AHPC-PEGn、[18F]6-fluoro-L-DOPA 前體 | 點(diǎn)擊化學(xué)、PROTAC、診斷顯像 |
| No. | Product Name | CAS No. | Quality Specification |
|---|---|---|---|
| 1 | m-PEG5-OH | 23778-52-1 | GC>99% Single homologous impurity: less than 0.1% |
| 2 | m-PEG6-OH | 23601-40-3 | |
| 3 | m-PEG7-OH | 4437-01-8 | |
| 4 | m-PEG8-OH | 25990-96-9 | HPLC-CAD>98% Single homologous impurity: less than 0.2 |
| 5 | m-PEG9-OH | 6048-68-6 | |
| 6 | m-PEG10-OH | 27425-92-9 | HPLC-CAD>98% Single homologous impurity: less than 0.2 |
| 7 | m-PEG11-OH | 2168540-65-4 | |
| 8 | m-PEG12-OH | 2050595-03-2 | |
| 9 | m-PEG24-OH | -- | HPLC-CAD>98% Single homologous impurity: less than 0.3 |
| No. | Product Name | CAS No. | Quality Specification |
|---|---|---|---|
| 1 | m-PEG2-NH2 | 31576-51-9 | GC>99% Single homologous impurity: less than 0.1% |
| 2 | m-PEG3-NH2 | 74654-07-2 | |
| 3 | m-PEG4-NH2 | 85030-56-4 | |
| 4 | m-PEG5-NH2 | 5498-83-9 | HPLC-CAD>98% Single homologous impurity: less than 0.2 |
| 5 | m-PEG6-NH2 | 184357-46-8 | |
| 6 | m-PEG7-NH2 | 170572-38-0 | HPLC-CAD>98% Single homologous impurity: less than 0.2 |
| 7 | m-PEG8-NH2 | 869718-81-0 | |
| 8 | m-PEG12-NH2 | 1977493-48-3 | |
| 9 | m-PEG24-NH2 | 2151823-08-2 | HPLC-CAD>98% Single homologous impurity: less than 0.3 |
| No. | Product Name | CAS No. | Quality Specification |
|---|---|---|---|
| 1 | m-PEG4-Br | 110429-45-3 | GC>98% Single homologous impurity: less than 0.1% |
| 2 | m-PEG5-Br | 854601-80-2 | |
| 3 | m-PEG6-Br | 125562-29-0 | |
| 4 | m-PEG7-Br | 104518-25-4 | |
| 5 | m-PEG8-Br | 1056881-04-9 | |
| 6 | m-PEG10-Br | N.A. | HPLC-CAD>98% Single homologous impurity: less than 0.15% |
| 7 | m-PEG12-Br | 1620461-89-3 | |
| 8 | m-PEG24-Br | N.A. | |
| 9 | m-PEG36-Br | N.A. | HPLC-CAD>98% Single homologous impurity: less than 0.5% |
